370 research outputs found

    Binding energies of hydrogen-like impurities in a semiconductor in intense terahertz laser fields

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    A detailed theoretical study is presented for the influence of linearly polarised intense terahertz (THz) laser radiation on energy states of hydrogen-like impurities in semiconductors. The dependence of the binding energy for 1s and 2p states on intensity and frequency of the THz radiation has been examined.Comment: 14 pages, 4 figure

    X-ray free-electron lasers

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    Core Hole Double-Excitation and Atomiclike Auger Decay in N<sub>2</sub>

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    Core hole decay spectra of the free N2 molecule show evidence for hitherto unobserved molecular resonances both below and above the K-shell photoionization threshold. Based on earlier calculations they are assigned to doubly excited neutral states which could not be seen below threshold in recent high resolution absorption spectra because of the more intense core-to-Rydberg excitations. By calculating the Auger spectrum of core-excited nitrogen atoms, we show that the features are atomiclike

    High-resolution C 1s photoelectron spectra of methane

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    The C 1s partial photoionization cross section and photoelectron angular distribution of methane (CH4) have been measured with high-energy resolution between threshold and 385 eV photon energy. From the analysis of the vibrational fine structure on the C 1s−1 photoelectron line a vibrational energy of 396±2 meV and an equilibrium bond length of 1.039(±0.001) Å for the CH+4 ion have been determined. The lifetime broadening was found to be 83(±10) meV. The weak feature in the photoabsorption cross section just above threshold does not influence the vibrational fine structure in a way typical for a shape resonance. We therefore suggest that it is due to doubly excited states of the type C (1s)−1(Val)−1(Ryd)1a(Ryd)1b, an assignment which is supported by recent Auger decay studies. Measurements of the shakeup structure revealed six satellite lines, one of which increases strongly in intensity at threshold, thus pointing to the existence of a conjugate shakeup process

    First Observation of Self-Amplified Spontaneous Emission in a Free-Electron Laser at 109 nm Wavelength

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    We present the first observation of Self-Amplified Spontaneous Emission (SASE) in a free-electron laser (FEL) in the Vacuum Ultraviolet regime at 109 nm wavelength (11 eV). The observed free-electron laser gain (approx. 3000) and the radiation characteristics, such as dependency on bunch charge, angular distribution, spectral width and intensity fluctuations all corroborate the existing models for SASE FELs.Comment: 6 pages including 6 figures; e-mail: [email protected]

    Violence in primary care: Prevalence and follow-up of victims

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    BACKGROUND: Primary care physicians underestimate the prevalence of domestic violence and community violence. Victims are therefore at risk of further episodes of violence, with psychological and physical consequences. We used an interview to assess the prevalence of domestic and community violence among Swiss natives and foreigners. In a follow-up study, we evaluated the consequences of the interview for the positive patients. METHODS: We evaluated the prevalence of violence by use of a questionnaire in an interview, in an academic general internal medicine clinic in Switzerland. In a follow-up, we evaluated the consequences of the interview for positive patients. The participants were 38 residents and 446 consecutive patients. Questionnaires were presented in the principal language spoken by our patients. They addressed sociodemographics, present and past violence, the security or lack of security felt by victims of violence, and the patients' own violence. Between 3 and 6 months after the first interview, we did a follow-up of all patients who had reported domestic violence in the last year. RESULTS: Of the 366 patients included in the study, 36 (9.8%) reported being victims of physical violence during the last year (physicians identified only 4 patients out of the 36), and 34/366 (9.3%) reported being victims of psychological violence. Domestic violence was responsible for 67.3% of the cases, and community violence for 21.8%. In 10.9% of the cases, both forms of violence were found. Of 29 patients who reported being victims of domestic violence, 22 were found in the follow-up. The frequency of violence had diminished (4/22) or the violence had ceased (17/22). CONCLUSION: The prevalence of violence is high; domestic violence is more frequent than community violence. There was no statistically significant difference between the Swiss and foreign patients' responses related to the rates of violence. Patients in a currently violent relationship stated that participating in the study helped them and that the violence decreased or ceased a few months later

    Mitochondrial genes are altered in blood early in Alzheimer's disease

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    Although mitochondrial dysfunction is a consistent feature of Alzheimer's disease in the brain and blood, the molecular mechanisms behind these phenomena are unknown. Here we have replicated our previous findings demonstrating reduced expression of nuclear-encoded oxidative phosphorylation (OXPHOS) subunits and subunits required for the translation of mitochondrial-encoded OXPHOS genes in blood from people with Alzheimer's disease and mild cognitive impairment. Interestingly this was accompanied by increased expression of some mitochondrial-encoded OXPHOS genes, namely those residing closest to the transcription start site of the polycistronic heavy chain mitochondrial transcript (MT-ND1, MT-ND2, MT-ATP6, MT-CO1, MT-CO2, MT-C03) and MT-ND6 transcribed from the light chain. Further we show that mitochondrial DNA copy number was unchanged suggesting no change in steady-state numbers of mitochondria. We suggest that an imbalance in nuclear and mitochondrial genome-encoded OXPHOS transcripts may drive a negative feedback loop reducing mitochondrial translation and compromising OXPHOS efficiency, which is likely to generate damaging reactive oxygen species
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